Chronic Fatigue Syndrome (CFS)/ Myalgic Encephalomyelitis (ME)
When fatigue is more than being tired.
When fatigue is more than being tired.
CFS/ME is a complex disorder marked by profound fatigue, post-exertional malaise, and unrefreshing sleep. Many patients with hypermobility, POTS, or MCAS also meet criteria for CFS/ME.
Severe fatigue
Post-exertional malaise (PEM)
Sleep disruption
Cognitive impairment (“brain fog”)
Muscle/joint pain
Dizziness (overlap with POTS)
No single test; diagnosis is clinical.
Rule out other causes.
Often overlaps with dysautonomia.
Pacing & energy management
Sleep hygiene
Mind-body support
Gentle movement under guidance
Strong overlap with POTS & MCAS.
Fatigue Tracker PDF
Pacing Guides
Support community links